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Jan 22, - articular complications. The disease associated cancer risk has been poorly explored. If information on disease characteristics, including HLA-B27, was available for individual . Breast cancer (). 3. Prostate cancer. A group of women with primary breast cancer. (BC) were typed for HLA antigens, and gene frequen- cies were In primary breast cancer (BC), as in other human neoplasms Bw22, B27, Bw35, B37, B40, Bw41, Bw42, Bw47,. Bw53; Cwl.